Material Safety Data
Sheet
Ninhydrin, reagent ACS
ACC# 01021
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Section 1 - Chemical Product and Company
Identification |
MSDS Name: Ninhydrin, reagent ACS
Catalog Numbers:
AC415720000, AC415720100, AC415720250
Synonyms: 1,2,3-Indantrione;
1,2,3-Triketohydrindene; 2,2-Dihydroxy-1,3-indandione;
2,2-Dihydroxy-1H-indene-1,3(2H)-dione; 1H-Indene-1,2,3-trione.
Company
Identification:
Acros
Organics N.V.
One Reagent
Lane
Fair Lawn, NJ
07410
For information in North America, call: 800-ACROS-01
For
emergencies in the US, call CHEMTREC: 800-424-9300
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Section 2 -
Composition, Information on Ingredients |
| CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
| 485-47-2 |
Ninhydrin |
100.0 |
207-618-1 |
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Section 3 - Hazards
Identification |
EMERGENCY OVERVIEW
Appearance: slightly yellow crystalline powder.
Warning!
Causes respiratory tract irritation. Harmful if swallowed. Causes eye and skin
irritation. May be harmful if absorbed through skin or if inhaled. Light
sensitive.
Target Organs: Eyes, skin, mucous membranes.
Potential Health Effects
Eye: Causes eye irritation.
Skin: Causes skin irritation. May cause skin sensitization,
an allergic reaction, which becomes evident upon re-exposure to this material.
May be harmful if absorbed through the skin. May cause reddening of the skin.
Ingestion: Harmful if swallowed. May cause irritation of
the digestive tract. The toxicological properties of this substance have not
been fully investigated.
Inhalation: The toxicological
properties of this substance have not been fully investigated. May be harmful if
inhaled. Inhalation of dust causes respiratory tract irritation with cough and
sore throat.
Chronic: No information found.
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Section 4 - First Aid
Measures |
Eyes: In case of contact, immediately flush eyes
with plenty of water for a t least 15 minutes. Get medical aid.
Skin: In case of contact, immediately flush skin with soap
and plenty of water. Remove contaminated clothing and shoes. Get medical aid if
symptoms occur. Wash clothing before reuse.
Ingestion: If
swallowed, do not induce vomiting unless directed to do so by medical personnel.
Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation: If inhaled, remove to fresh air. If not
breathing, give artificial respiration. If breathing is difficult, give oxygen.
Get medical aid.
Notes to Physician: Treat symptomatically
and supportively.
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Section 5 - Fire
Fighting Measures |
General
Information: As in any fire, wear a self-contained breathing apparatus
in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective
gear. Dusts at sufficient concentrations can form explosive mixtures with air.
Extinguishing Media: Use water spray, dry chemical, carbon
dioxide, or chemical foam.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits,
Lower:Not available.
Upper: Not available.
NFPA
Rating: (estimated) Health: 2; Flammability: 1; Instability: 0
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Section 6 -
Accidental Release Measures |
General
Information: Use proper personal protective equipment as indicated in
Section 8.
Spills/Leaks: Vacuum or sweep up material and
place into a suitable disposal container. Avoid generating dusty conditions.
Provide ventilation.
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Section 7 - Handling
and Storage |
Handling: Wash thoroughly after handling. Remove
contaminated clothing and wash before reuse. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid contact with eyes, skin, and
clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage: Do not store in direct sunlight. Store in a
tightly closed container. Store in a cool, dry, well-ventilated area away from
incompatible substances. Store protected from light. Refrigeration has been
recommended.
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Section 8 - Exposure
Controls, Personal Protection |
Engineering
Controls: Facilities storing or utilizing this material should be
equipped with an eyewash facility and a safety shower. Use adequate ventilation
to keep airborne concentrations low.
Exposure Limits
| Chemical Name |
ACGIH |
NIOSH |
OSHA -
Final PELs |
| Ninhydrin |
none listed |
none listed |
none listed
|
OSHA Vacated PELs: Ninhydrin: No
OSHA Vacated PELs are listed for this chemical.
Personal Protective
Equipment
Eyes: Wear appropriate protective
eyeglasses or chemical safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin
exposure.
Clothing: Wear appropriate protective clothing to
prevent skin exposure.
Respirators: Follow the OSHA respirator
regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits
are exceeded or if irritation or other symptoms are experienced.
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Section 9 - Physical
and Chemical Properties |
Physical State:
Crystalline powder
Appearance: slightly yellow
Odor:
characteristic odor
pH: Not available.
Vapor Pressure:
Negligible.
Vapor Density: 6.16 (air=1)
Evaporation
Rate:Not applicable.
Viscosity: Not available.
Boiling
Point: Not available.
Freezing/Melting Point:466 deg F (dec)
Decomposition Temperature:466 deg F
Solubility: Soluble in
water.
Specific Gravity/Density:0.86
Molecular
Formula:C9H6O4
Molecular Weight:178.14
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Section 10 -
Stability and Reactivity |
Chemical
Stability: Stable under normal temperatures and pressures. May discolor on
exposure to light. Ninhydrin becomes anhydrous with reddening at 257°F, swells
at 282°F and decomposes at 466°F. Ninhydrin is sensitive to prolonged exposure
to light. UV spectrophotometric stability screening indicates that solutions of
this compound in ethanol are stable for at least 24 hours.
Conditions to
Avoid: High temperatures, light, dust generation.
Incompatibilities
with Other Materials: Strong oxidizing agents, bases, amines.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
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Section 11 -
Toxicological Information |
RTECS#:
CAS# 485-47-2: NK5425000
LD50/LC50:
Not available.
Oral, rat, LDLo = 250 mg/kg.
Carcinogenicity:
CAS# 485-47-2: Not listed by ACGIH, IARC, NTP, or
CA Prop 65.
Epidemiology: No information found
Teratogenicity: No information found
Reproductive Effects:
No information found
Mutagenicity: No information found
Neurotoxicity: No information found
Other Studies:
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Section 12 -
Ecological Information |
Ecotoxicity: No
data available. No information available.
Environmental: No
information available.
Physical: Log P (octanol-water): 0.67
Other: No information available.
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Section 13 - Disposal
Considerations |
Chemical waste generators
must determine whether a discarded chemical is classified as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR
Parts 261.3. Additionally, waste generators must consult state and local
hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
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Section 14 -
Transport Information |
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US
DOT |
Canada
TDG |
| Shipping Name: |
Not regulated as a hazardous material |
No information available. |
| Hazard Class: |
|
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| UN Number: |
|
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| Packing Group: |
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Section 15 -
Regulatory Information |
US
FEDERAL
TSCA
CAS#
485-47-2 is listed on the TSCA inventory.
Health & Safety Reporting
List
None of the chemicals are on the
Health & Safety Reporting List.
Chemical Test
Rules
None of the chemicals in this product
are under a Chemical Test Rule.
Section
12b
None of the chemicals are listed under
TSCA Section 12b.
TSCA Significant New Use
Rule
None of the chemicals in this material
have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding
RQs
None of the chemicals in this material
have an RQ.
SARA Section 302 Extremely Hazardous
Substances
None of the chemicals in this
product have a TPQ.
SARA Codes
CAS #
485-47-2: immediate.
Section 313 No
chemicals are reportable under Section 313.
Clean Air
Act:
This material does not contain any
hazardous air pollutants.
This material does
not contain any Class 1 Ozone depletors.
This
material does not contain any Class 2 Ozone depletors.
Clean Water
Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are
listed as Priority Pollutants under the CWA.
None of the chemicals in this product are
listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this
product are considered highly hazardous by OSHA.
STATE
CAS# 485-47-2 is not present
on state lists from CA, PA, MN, MA, FL, or NJ.
California Prop
65
California No Significant Risk Level: None of the chemicals in
this product are listed.
European/International
Regulations
European Labeling in Accordance with EC
Directives
Hazard Symbols:
XN
Risk Phrases:
R 22 Harmful if
swallowed.
R 36/37/38 Irritating to eyes,
respiratory system and skin.
Safety
Phrases:
S 26 In case of contact with eyes,
rinse immediately with plenty of
water and
seek medical advice.
S 28A After contact with
skin, wash immediately with plenty of water
.
WGK (Water
Danger/Protection)
CAS# 485-47-2: 2
Canada - DSL/NDSL
CAS# 485-47-2 is
listed on Canada's DSL List.
Canada -
WHMIS
This product has a WHMIS
classification of D1B, D2B.
This product has been classified in accordance
with the hazard criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian
Ingredient Disclosure List
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Section 16 -
Additional Information |
MSDS Creation Date:
9/23/1998
Revision #5 Date: 10/03/2005
The information above is
believed to be accurate and represents the best information currently available
to us. However, we make no warranty of merchantability or any other warranty,
express or implied, with respect to such information, and we assume no liability
resulting from its use. Users should make their own investigations to determine
the suitability of the information for their particular purposes. In no event
shall Fisher be liable for any claims, losses, or damages of any third party or
for lost profits or any special, indirect, incidental, consequential or
exemplary damages, howsoever arising, even if Fisher has been advised of the
possibility of such damages.