Material Safety Data
Sheet
Acetanilide
ACC# 00115
|
Section 1 - Chemical Product and Company
Identification |
MSDS Name: Acetanilide
Catalog Numbers: AC150810010, AC150810050, AC150812500,
AC150815000, AC400050250, AC400051000, S79879-1, O1013-250
Synonyms:
N-Phenylacetamide
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance,
call: 800-424-9300
For International CHEMTREC assistance, call:
703-527-3887
|
Section 2 -
Composition, Information on Ingredients |
| CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
| 103-84-4 |
Acetanilide |
100 |
203-150-7 |
|
Section 3 - Hazards
Identification |
EMERGENCY OVERVIEW
Appearance: white glistening crystals. solid.
Warning!
May cause eye, skin, and respiratory tract irritation. May cause allergic skin
reaction. May be harmful if swallowed. May cause central nervous system effects.
May cause blood abnormalities.
Target Organs: Blood,
kidneys, central nervous system, skin.
Potential Health
Effects
Eye: Dust may cause mechanical
irritation.
Skin: May cause skin irritation. May cause skin
sensitization, an allergic reaction, which becomes evident upon re-exposure to
this material.
Ingestion: Harmful if swallowed. May cause
irritation of the digestive tract. May cause kidney damage. May cause
methemoglobinemia, cyanosis (bluish discoloration of skin due to deficient
oxygenation of the blood), convulsions, and death. Human systemic effects by
ingestion may include: visual field changes, tinnitus, and nausea or vomiting.
May cause hallucinations and distorted perceptions. Ingestion may cause kidney
damage including acute tubular necrosis and acute renal failure.
Inhalation: May cause respiratory tract irritation. May
cause methemoglobinemia, cyanosis (bluish discoloration of skin due to deficient
oxygenation of the blood), convulsions, tachycardia, dyspnea (labored
breathing), and death. May cause effects similar to those described for
ingestion. Coal tar analgetics including acetanilide are depressants of the
central nervous system.
Chronic: Chronic exposure may cause
effects similar to those of acute exposure.
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Section 4 - First Aid
Measures |
Eyes: Flush eyes with plenty of water for at least
15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Immediately flush skin with plenty
of water for at least 15 minutes while removing contaminated clothing and shoes.
Wash clothing before reuse.
Ingestion: Call a poison
control center. If swallowed, do not induce vomiting unless directed to do so by
medical personnel. Never give anything by mouth to an unconscious person. Get
medical aid.
Inhalation: Get medical aid immediately.
Remove from exposure and move to fresh air immediately. If not breathing, give
artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician: Treat symptomatically and supportively.
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Section 5 - Fire
Fighting Measures |
General
Information: As in any fire, wear a self-contained breathing apparatus
in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective
gear. Will burn if involved in a fire. Dust can be an explosion hazard when
exposed to heat or flame. Vapors may be heavier than air. They can spread along
the ground and collect in low or confined areas.
Extinguishing
Media: For small fires, use water spray, dry chemical, carbon dioxide
or chemical foam. Use water spray to cool fire-exposed containers.
Flash
Point: 173 deg C ( 343.40 deg F)
Autoignition Temperature: 545
deg C ( 1,013.00 deg F)
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated)
Health: 2; Flammability: 1; Instability: 0
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Section 6 -
Accidental Release Measures |
General
Information: Use proper personal protective equipment as indicated in
Section 8.
Spills/Leaks: Vacuum or sweep up material and
place into a suitable disposal container. Clean up spills immediately, observing
precautions in the Protective Equipment section. Avoid generating dusty
conditions. Provide ventilation.
|
Section 7 - Handling
and Storage |
Handling: Wash thoroughly after handling. Use with
adequate ventilation. Minimize dust generation and accumulation. Avoid contact
with eyes, skin, and clothing. Avoid ingestion and inhalation.
Storage: Keep away from heat and flame. Store in a tightly
closed container. Keep from contact with oxidizing materials. Store in a cool,
dry, well-ventilated area away from incompatible substances. Keep away from
strong bases.
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Section 8 - Exposure
Controls, Personal Protection |
Engineering
Controls: Facilities storing or utilizing this material should be
equipped with an eyewash facility and a safety shower. Use adequate general or
local explosion-proof ventilation to keep airborne levels to acceptable levels.
Exposure Limits
| Chemical Name |
ACGIH |
NIOSH |
OSHA -
Final PELs |
| Acetanilide |
none listed |
none listed |
none listed
|
OSHA Vacated PELs: Acetanilide:
No OSHA Vacated PELs are listed for this chemical.
Personal
Protective Equipment
Eyes: Wear appropriate
protective eyeglasses or chemical safety goggles as described by OSHA's eye and
face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent
skin exposure.
Respirators: Follow the OSHA respirator regulations
found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or
European Standard EN 149 approved respirator if exposure limits are exceeded or
if irritation or other symptoms are experienced.
|
Section 9 - Physical
and Chemical Properties |
Physical State:
Solid
Appearance: white glistening crystals.
Odor: Not
available.
pH: Not available.
Vapor Pressure: 1 mm Hg @237
deg F
Vapor Density: 4.65 (air=1)
Evaporation
Rate:Negligible.
Viscosity: Not available.
Boiling
Point: 304 deg C @ 760 mm Hg
Freezing/Melting Point:113 - 115 deg
C
Decomposition Temperature:Not available.
Solubility:
Slightly soluble.
Specific Gravity/Density:1.21
Molecular
Formula:C8H9NO
Molecular Weight:135.17
|
Section 10 -
Stability and Reactivity |
Chemical
Stability: Stable.
Conditions to Avoid: Dust generation.
Incompatibilities with Other Materials: Strong oxidizing agents,
strong bases.
Hazardous Decomposition Products: Carbon monoxide,
oxides of nitrogen, carbon dioxide.
Hazardous Polymerization: Has not
been reported.
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Section 11 -
Toxicological Information |
RTECS#:
CAS# 103-84-4: AD7350000
LD50/LC50:
CAS# 103-84-4:
Oral,
mouse: LD50 = 1210 mg/kg;
Oral, rat: LD50 = 800
mg/kg;
.
Carcinogenicity:
CAS# 103-84-4: Not listed by
ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology: No information
found
Teratogenicity: No information found
Reproductive
Effects: No information found
Mutagenicity: Micronucleus
test(Intraperitoneal,mouse) = 50 mg/kg
Neurotoxicity: No information
found
Other Studies:
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Section 12 -
Ecological Information |
Ecotoxicity:
Fish: Bluegill/Sunfish: LC50 = 100 mg/L; 96 Hr.; Static, 23 degrees C No
data available.
Environmental: An estimated BCF value of 4.5 was
calculated for acetanilide, using an experimental log Kow of 1.16. According to
a classification scheme, this BCF value suggests that bioconcentration in
aquatic organisms is low.
Physical: Acetanilide is not expected to
undergo hydrolysis or direct photolysis in the environment due to the lack of
functional groups to hydrolyze or absorb UV light.
Other: No
information available.
|
Section 13 - Disposal
Considerations |
Chemical waste generators
must determine whether a discarded chemical is classified as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR
Parts 261.3. Additionally, waste generators must consult state and local
hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
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Section 14 -
Transport Information |
|
US
DOT |
Canada
TDG |
| Shipping Name: |
Not regulated as a hazardous material |
No information available. |
| Hazard Class: |
|
|
| UN Number: |
|
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| Packing Group: |
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Section 15 -
Regulatory Information |
US
FEDERAL
TSCA
CAS#
103-84-4 is listed on the TSCA inventory.
Health & Safety Reporting
List
None of the chemicals are on the
Health & Safety Reporting List.
Chemical Test
Rules
None of the chemicals in this product
are under a Chemical Test Rule.
Section
12b
None of the chemicals are listed under
TSCA Section 12b.
TSCA Significant New Use
Rule
None of the chemicals in this material
have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding
RQs
None of the chemicals in this material
have an RQ.
SARA Section 302 Extremely Hazardous
Substances
None of the chemicals in this
product have a TPQ.
SARA Codes
CAS #
103-84-4: immediate, delayed.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does
not contain any hazardous air pollutants.
This
material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2
Ozone depletors.
Clean Water
Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are
listed as Priority Pollutants under the CWA.
None of the chemicals in this product are
listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this
product are considered highly hazardous by OSHA.
STATE
CAS# 103-84-4 can be found on
the following state right to know lists: Pennsylvania, Massachusetts.
California Prop 65
California No Significant Risk Level:
None of the chemicals in this product are listed.
European/International Regulations
European
Labeling in Accordance with EC Directives
Hazard
Symbols:
XN
Risk
Phrases:
R 22 Harmful if swallowed.
Safety Phrases:
WGK (Water
Danger/Protection)
CAS# 103-84-4: 1
Canada - DSL/NDSL
CAS# 103-84-4 is
listed on Canada's DSL List.
Canada -
WHMIS
This product has a WHMIS
classification of D2B.
This product has been classified in accordance with
the hazard criteria of the Controlled Products Regulations and the MSDS contains
all of the information required by those regulations.
Canadian Ingredient
Disclosure List
|
Section 16 -
Additional Information |
MSDS Creation Date:
5/04/1999
Revision #4 Date: 10/03/2005
The information above is
believed to be accurate and represents the best information currently available
to us. However, we make no warranty of merchantability or any other warranty,
express or implied, with respect to such information, and we assume no liability
resulting from its use. Users should make their own investigations to determine
the suitability of the information for their particular purposes. In no event
shall Fisher be liable for any claims, losses, or damages of any third party or
for lost profits or any special, indirect, incidental, consequential or
exemplary damages, howsoever arising, even if Fisher has been advised of the
possibility of such damages.